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CHART Publication – Modifying effects of home medication use on acute kidney-related morbidity due to elevated ambient heat exposure

May 30, 2025

CHART investigators have published the article “ Case-crossover assessment of the modifying effects of home medication use on acute kidney-related morbidity due to elevated ambient heat exposure in Atlanta, GA, from 2013 to 2019“. The article focuses on how elevated ambient temperatures increase the risk for acute kidney-related morbidity, and medication use may increase vulnerability to heat exposure. This study examines whether medication use, and combination medication use (ie, polypharmacy), modifies the risk for temperature-related volume depletion (VD) and acute kidney injury (AKI).

Zachary McCann, Haisu Zhang, Kenneth Mueller, Yaoyao Qian, Morgan Lane, Rohan Dsouza, E Jennifer Weil, Stefanie Ebelt, Noah Scovronick, Howard H Chang – Case-crossover assessment of the modifying effects of home medication use on acute kidney-related morbidity due to elevated ambient heat exposure in Atlanta, GA, from 2013 to 2019: BMJ Public Health 2025;3:e001703.